Improved method of producing lycopene through the...

C - Chemistry – Metallurgy – 12 – P

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C12P 23/00 (2006.01) A23L 1/275 (2006.01) A23L 1/30 (2006.01) A23L 1/302 (2006.01) A61K 9/107 (2006.01) A61K 9/14 (2006.01) C09B 61/00 (2006.01)

Patent

CA 2472401

The invention relates to a method of fermenting selected strains of B. Trispora which can be used to achieve lycopene production levels greater than current levels. The isolation, purification and formulation methods can be applied to any natural lycopene source and, in particular, to submerged cultures of Blakeslea-, Choanephora-, Phycomyces- or Mucor-type Mucorales fungi. The extraction method enables the recovery method to be simplified and the purity of the product to be increased with respect to standard methods. The formulation methods provide high added value owing to the fact that they can be used to obtain stabilised lycopene preparations which can be used directly in the food and pharmaceutical fields.

L'invention concerne un procédé de fermentation de souches sélectionnées de B. Trispora permettant d'atteindre des niveaux de production de lycopène supérieurs aux niveaux actuels. Les procédés d'isolement, de purification et de formulation peuvent s'appliquer à n'importe quelle source naturelle de lycopène, et spécialement aux cultures submergées de champignons mucorales des genres Blakeslea, Choanephora, Phycomyces ou Mucor. Le procédé d'extraction permet de simplifier le processus de récupération et d'augmenter la pureté du produit par rapport aux procédés classiques. Les procédés de formulation permettent d'obtenir une haute valeur ajoutée puisqu'ils permettent d'obtenir des préparations stabilisées de lycopène pouvant être utilisées directement dans les domaines alimentaire et pharmaceutique.

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