Improved method of treating degenerative spinal disorders

A - Human Necessities – 61 – L

Patent

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A61L 27/54 (2006.01) A61B 17/70 (2006.01) A61F 2/44 (2006.01) A61K 39/395 (2006.01) A61L 27/52 (2006.01) A61P 19/00 (2006.01) A61P 29/00 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2606084

The present invention describes methods for treating a degenerative intervertebral disc disorder comprising implanting a disc stabilization device into a subject and administering at least one therapeutic agent which promotes healing of the disc to the subject. The invention also includes methods of promoting healing of damaged or degenerated intervertebral discs comprising decreasing the load of the disc through a disc stabilization device and inhibiting the inflammatory process. Also described are hydrogels for use in combination with extradiscal stabilization devices, as intradiscal stabilization devices, as drug carriers, and as combinations thereof.

La présente invention concerne des méthodes destinées à traiter une affection dégénérative d'un disque intervertébral et consistant à implanter un dispositif de stabilisation discale dans le corps d'un sujet et à administrer à ce sujet au moins un agent thérapeutique favorisant la réparation du disque. L'invention concerne également des méthodes destinées à favoriser la réparation de disques endommagés ou présentant une dégénérescence et consistant à réduire la charge exercée sur le disque au moyen d'un dispositif de stabilisation discale et à inhiber le processus inflammatoire. L'invention se rapporte en outre à des hydrogels destinés à être utilisés en combinaison avec des dispositifs de stabilisation extra-discaux comme dispositifs de stabilisation intra-discaux, comme supports de médicaments, ou les deux.

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