Improved methods for oligonucleotide synthesis

Details Improved methods for oligonucleotide synthesis Improved methods for oligonucleotide synthesis

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01)

Patent

CA 2222440

Improved methods for solution-phase synthesis of purified short-chain oligonucleotide coupling units, such as dimers, trimers, and tetramers, suitable for use in solution-phase or solid-phase oligonucleotide synthesis are provided.

L'invention porte sur des procédés améliorés de synthèse en phase de solution d'unités de couplage purifiées d'oligonucléotides à chaîne courte tels que des dimères, trimères et tétramères pouvant servir à la synthèse en phase de solution et en phase solide d'oligonucléotides.

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