Improved methods for the determination and adjustment of...

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A61K 31/495 (2006.01) A61K 31/00 (2006.01) A61K 31/13 (2006.01) A61K 31/137 (2006.01) A61K 31/15 (2006.01) A61K 31/165 (2006.01) A61K 31/166 (2006.01) A61K 31/195 (2006.01) A61K 31/221 (2006.01) A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/435 (2006.01) A61K 31/439 (2006.01) A61K 31/4515 (2006.01) A61K 31/454 (2006.01) A61K 31/46 (2006.01) A61K 31/475 (2006.01) A61K 31/48 (2006.01) A61K 31/5415 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 31/5513

Patent

CA 2152508

A method for detecting abnomalities in prolactin daily rhythms. The method includes the step of comparing a prolactin profile of the test subjects over a predetermined period to a predetermined standard prolacting profile of healthy subjects. The method also includes the step of determining whether the test subjects have an abnormal daily prolacting rhythm by assertaining the prolactin level during waking hours and sleeptime. The determination is made to see if the test subjects have a prolactin level that is greater than 1 SEM above the normal prolactin profile of healthy subjects at waking hours and at sleep time, a prolactin level that is at least one SEM lower than the normal prolactin profile of the healthy subjects. Methods are also provided for determining adjustments needed to an abnormal prolactin profile to cause it to conform to the prolactin profile of a healthy subject.

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