C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 1/18 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2276548
Disclosed are improvements in methods for the isolation of endotoxin-binding proteins which are secreted by transfected host cells in appropriate cell culture media. In its preferred embodiments, the invention comprises addition of a cation exchange material to the media as the means of increasing the yield of recombinant endotoxin- binding proteins, such as bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein.
Mbm Intellectual Property Law Llp
Xoma Corporation
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