Improved modulators of coagulation factors

Details Improved modulators of coagulation factors Improved modulators of coagulation factors

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2563176

The invention provides improved nucleic acid ligands that inhibit coagulation and improved modulators of the nucleic acids to provide ideal modulators of coagulation. These improved nucleic acids acids and modulators are particularly useful for inhibiting coagulation in a host undergoing a therapeutic regime such as surgery or coronary artery bypass.

L'invention concerne des ligands d'acides nucléiques améliorés inhibant la coagulation et des modulateurs améliorés des acides nucléiques qui permettent d'obtenir des modulateurs de coagulation idéaux. Ces acides nucléiques et ces modulateurs améliorés sont particulièrement utiles pour inhiber la coagulation chez un hôte suivant un régime thérapeutique tel qu'une intervention chirurgicale ou un pontage aortocoronarien.

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