Improved nucleic acid modifying enzymes

Details Improved nucleic acid modifying enzymes Improved nucleic acid modifying enzymes

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) C07K 1/00 (2006.01) C07K 14/00 (2006.01) C07K 19/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2409417

This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the ability of the enzyme to bind and catalytically modify the nucleic acid.

L'invention concerne une génération améliorée de nouvelles enzymes modificatrices de l'acide nucléique. L'amélioration consiste à fusionner un domaine de liaison d'acide nucléique de séquence non-spécifique avec l'enzyme d'une manière qui renforce la capacité de l'enzyme de lier et de modifier catalytiquement l'acide nucléique.

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