Improved osteoinductive materials

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/34 (2006.01) A61L 27/56 (2006.01) C07K 14/475 (2006.01)

Patent

CA 2519174

The present invention relates to an osteoinductive materials comprising a matrix materials with morphogenetic protein (s) absorbed on inner or outer surfaces of this matrix material, wherein the osteoinductive material is obtainable by contacting the matrix material and the morphogenic protein (s) under conditions of pH and ionic concentration to keep protein stable and dissolved in a solution until dried and thereby allowing that the matrix material becomes evenly coated with the morphogenic protein (s).

L'invention concerne des matériaux ostéoinducteurs améliorés comprenant des matériaux matriciels et des protéines morphogénétiques, qui en fonction de la matière d'un sujet peuvent être des protéines dimères ou monomères. Ces matériaux ostéoinducteurs de l'invention possèdent des propriétés améliorées. L'invention concerne également des procédés permettant de produire les matériaux ostéoinducteurs respectifs améliorés.

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