Improved paclitaxel-based antitumor formulation

Details Improved paclitaxel-based antitumor formulation Improved paclitaxel-based antitumor formulation

A - Human Necessities

61

K

A61K 9/51 (2006.01) A61K 9/107 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/335 (2006.01) A61K 31/337 (2006.01) A61K 47/42 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2423884

Antitumor formulation based on nanoparticles of paclitaxel and human serum al- bumin as obtained by the addition of a biocompatible acid to an aqueous albumin solution before this is mixed with paclitaxel during the nanoparticle production process, the injectable solutions of this formulation having a pH between 5.4 and 5.8 and having stability and inalterability with time.

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