A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/401 (2006.01) A61K 47/34 (2006.01)
Patent
CA 2612742
The present invention relates to the formulation of solid dosage forms for oral or sub-lingual administration comprising a therapeutically effective amount of an ACE inhibitor or a paharmaceutical acceptable salt thereof, and especially Fosinopril or Trandolapril or salts thereof, in combination with inorganic silica polymer such as Dimethicone, and a process for the preparation thereof by direct compression.
La présente invention concerne une préparation de formes posologiques solides destinées à une administration orale ou sublinguale, comprenant une quantité thérapeutiquement efficace d'un inhibiteur ACE ou d'un sel pharmaceutiquement acceptable de ce dernier, et notamment du Fosinopril ou du Trandolapril ou des sels de ces derniers, en combinaison avec un polymère de silice inorganique tel que du Diméthicone. L'invention concerne également un procédé de préparation desdites formes par compression directe.
Bikiaris Dimitrios
Karavas Evangelos
Kotzagiorgis Evangelos
Koutris Efthimios
Dimock Stratton Llp
Pharmathen S.a.
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