C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 303/22 (2006.01) C07C 303/32 (2006.01)
Patent
CA 2529269
The present invention is directed to methods of preparation of sulfonate derivatized compounds, e.g., 3-amino-l-propanesulfonic acid and 1,3- propanedisulfonic acid disodium salt with increased purity, with reduced potential for toxic by-products, and that are pharmaceutically useful, e.g., for the treatment of amyloidosis.
La présente invention se rapporte à des procédés de préparation de composés de sulfonate dérivés, par exemple l'acide 3-amino-1-propanesulfonique et un sel de disodium d'acide 1,3-propanedisulfonique de pureté accrue, ces composés présentant un potentiel réduit de génération de produits secondaires toxiques et étant pharmaceutiquement utiles, par exemple pour le traitement de l'amylose.
Kong Xianqi
Migneault David
Wu Xinfu
Gowling Lafleur Henderson Llp
Kiacta Sarl
Neurochem (international) Limited
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