Improved process

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 259/06 (2006.01)

Patent

CA 2740559

The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.

La présente invention porte sur un procédé amélioré pour la préparation de l'ingrédient pharmaceutique actif, vorinostat. En particulier, l'invention porte sur un procédé pour préparer du vorinostat sensiblement exempt d'impuretés.

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