C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 7/00 (2006.01) C12N 11/10 (2006.01) C12P 13/00 (2006.01)
Patent
CA 2432190
This invention relates to an improved process for preparing a carboxylic acid from the corresponding nitrile using a nitrilase catalyst. More particularly, the instant invention converts 2-methylglutaronitrile to 4-cyanopentanoic acid in aqueous solution using an enzyme catalyst having an nitrilase activity, immobilized in alginate, and crosslinked with glutaraldehyde and polyethylenimine.
La présente invention concerne un procédé de préparation amélioré d'un acide carboxylique à partir du nitrile correspondant, à l'aide d'un catalyseur nitrilase. La présente invention concerne plus particulièrement la transformation du 2-méthylglutaronitrile en acide 4-cyanopentanoique en solution aqueuse, à l'aide d'un catalyseur enzymatique à activité nitrilase immobilisé dans l'alginate et réticulé avec du glutaraldéhyde et du polyéthylène imine.
Dicosimo Robert
Fall0n Robert D.
Gavagan John E.
Bennett Jones Llp
E. I. Du Pont de Nemours And Company
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