A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/38 (2006.01) A61L 27/36 (2006.01)
Patent
CA 2183263
Processes for the non-glutaraldehyde fixation of a prosthesis to be implanted in a mammal whereby the prosthesis is fixed by employing coupling agents and/or cross-linking agents to form amide linkages between and within the proteinaceous molecules of the prosthetic tissue. The disclosed processes prevent or retard calcification and result in a nontoxic product which does not cause inflammation, providing prostheses that are well-suited for implantation in a mammal.
La présente invention porte sur des procédés de fixation, sans glutaraldehyde, d'une prothèse destinée à être implantée chez un mammifère, opération au cours de laquelle la prothèse est fixée à l'aide d'agents de couplage et/ou d'agents de réticulation pour former des liaisons amide entre les molécules protéiques du tissu prothétique et à l'intérieur de celles-ci. Les procédés selon l'invention empêchent ou retardent la calcification et donnent un produit non toxique ne provoquant aucune inflammation, d'où la possibilité de l'utiliser pour obtenir des prothèses se prêtant à l'implantation chez un mammifère.
Girardot Jean-Marie
Girardot Marie-Nadia
Biomedical Design Inc.
Macrae & Co.
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