C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/22 (2006.01) C07C 227/22 (2006.01) C07C 227/32 (2006.01) C07D 305/12 (2006.01)
Patent
CA 2120811
Manufacturing of L-(-)-carnitine from starting compounds containing an asymmetrical carbon atom having a configuration opposite to that of L-(-)-carnitine is set out utilizing as the starting compound D-(+)- carnitinamide or D-(+)-carnitinenitrile which is then converted to acyl D-(+)-carnitinenitrile or acyl D-(+)-carnitinamide followed by acid hydrolysis to D-(+)-carnitine followed by lactonizing to the lactone of L-(-)-carnitine and finally converting the resulting product to L-(-)-carnitine.
Castagnani Roberto
de Angelis Francesco
de Witt Paolo
Giannessi Fabio
Misiti Domenico
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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