C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/22 (2006.01) C07C 227/14 (2006.01) C07C 227/18 (2006.01) C07C 227/22 (2006.01) C07C 227/32 (2006.01) C07C 309/65 (2006.01) C07C 323/66 (2006.01)
Patent
CA 2120812
The manufacture of L-(-)-carnitine from a starting compound containing an asymmetrical carbon atom having a configuration opposite to that of L-(-)-carnitine is set out. The starting compound is D-(+)-carnitinamide which is converted into an ester followed by conversion of the ester to an acyl derivative followed by acid hydrolysis of the COOR group to a carboxylic group to obtain acyl D-(+)-carnitine followed by lactonizing the acyl D-(+)-carnitine to a lactone of L-(-)-carnitine followed by a conversion of the lactone to L-(-)-carnitine.
Bernabei Ida
de Angelis Francesco
Giannessi Fabio
Scafetta Nazareno
Tinti Maria Ornella
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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