Improved process for the measurement of non-transferrin...

G - Physics – 01 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01N 33/90 (2006.01)

Patent

CA 2407508

Method for determining the content of non-transferrin-bound iron (NTBI) and/or chelator accessible iron in samples, particularly serum samples, which comprises two stages. Each stage comprises contacting the sample with a reagent and measuring the fluorescence of the contacted sample, wherein in the first stage the reagent is a fluorescent probe and in the second stage the reagent is a fluorescent probe with the addition of a large amount of a Fe chelator. The fluorescent probe that is used in the second stage may be the same that is used in the first stage and may comprise a fluorescent marker combined with a Fe chelator. The fluorescent marker may be fluorescein, or derivatives of fluorescein, coumarin and BODIPY.

L'invention concerne une méthode de détermination de la teneur en fer non lié à la transferrine (NTBI), et/ou de fer pouvant être chélaté, dans des échantillons, en particulier dans des échantillons de sérum, qui comprend deux stades. Dans chaque stade on met en contact l'échantillon avec un réactif et on mesure la fluorescence de l'échantillon, le réactif étant une sonde fluorescente dans le premier stade, et une sonde fluorescente contenant une grande quantité d'un agent chélatant le fer dans le second stade. La sonde fluorescente utilisée dans les deux stades peut être la même et peut comporter un marqueur fluorescent combiné avec un agent chélatant le fer. Le marqueur fluorescent peut être de la fluorescéine, ou des dérivés de la fluorescéine, de la coumarine et du BODIPY?®¿.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Improved process for the measurement of non-transferrin... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Improved process for the measurement of non-transferrin..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Improved process for the measurement of non-transferrin... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1811795

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.