Improved process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 489/08 (2006.01) B01J 23/46 (2006.01)

Patent

CA 2637610

The present invention is directed to the conversion of a 6-keto morphinan to a 6-alpha-hydroxy morphinan in the presence of a ruthenium, rhodium, or iridium asymmetric catalyst and a hydrogen source.

La présente invention concerne la conversion d'une 6-céto morphinane en une 6-alpha-hydroxy morphinane en présence d'un catalyseur asymétrique de ruthénium, rhodium ou iridium et d'une source d'hydrogène.

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