Improved process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 513/04 (2006.01) A61K 31/542 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2666405

Disclosed herein is an improved process for the preparation of (R)-(+)-4- (Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6- sulfonamide- 1,1 -dioxide (Brinzolamide) and novel intermediates thereof.

L'invention concerne un procédé perfectionné pour la préparation de (R)-(+)-4-(éthylamino)-3,4-dihydro-2-(3-méthoxypropyl)-2H-thiéno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxyde (Brinzolamide) et de nouveaux intermédiaires de celui-ci.

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