Improved process for the preparation of ramipril

Details Improved process for the preparation of ramipril Improved process for the preparation of ramipril

C - Chemistry, Metallurgy

07

D

C07D 209/52 (2006.01)

Patent

CA 2363658

A process for separating diastereomeric mixtures of compounds of formula 1 and formula 2 Image wherein R1 = H or R1 denotes a carboxyl-esterifying group selected from C1-C6 alkyl and C7-C8 aralkyl, by treating the mixture of 1 and 2 with a solvent or mixture of solvents to obtain a substantially pure compound of formula 1.

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