Improved process for the synthesis of...

Details Improved process for the synthesis of... Improved process for the synthesis of...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) C07D 333/70 (2006.01)

Patent

CA 2172382

An improved process for the preparation of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides is described where a cinnamic acid is converted in the presence of thionyl chloride and a 4-N,N'-disubstituted aminopyridine in one step to the desired product.

L'invention concerne un procédé amélioré permettant de préparer des chlorures de 3-chlorobenzo[b]thiophène-2-carbonyle, selon lequel un acide cinnamique est transformé, en présence de chlorure de thionyle et d'aminopyridine à disubstitution 4-N-,N' en une seule étape, pour obtenir le produit voulu.

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