A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/08 (2006.01) A61K 38/06 (2006.01) C07K 5/093 (2006.01) C07K 5/097 (2006.01) C07K 5/103 (2006.01) C07K 5/113 (2006.01) C07K 7/06 (2006.01) C07K 7/14 (2006.01)
Patent
CA 2323237
The present invention provides methods and kits for mitigating radiation induced tissue damage, improving the effectiveness of radiation therapy, to support bone marrow transplantation, and promoting megakaryocyte production and mobilization and platelet production, each method comprising the administration of an effective amount of angiotensinogen, angiotensin I(AI), AI analogues, AI fragments and analogues thereof, angiotensin II (AII), AII analogues, AII fragments or analogues thereof or All AT2 type 2 receptor agonists.
La présente invention concerne des méthodes et trousses destinées à atténuer les dégâts causés aux tissus par un rayonnement, à améliorer l'efficacité de la radiothérapie, à faciliter une greffe de moelle osseuse et à favoriser la production et la mobilisation de mégacaryocytes et la production de plaquettes; chaque méthode consiste à administrer une quantité effective d'angiotensinogène, d'angiotensine I (AI), d'analogues d'AI, de fragments d'AI et de leurs analogues, d'angiotensine II (AII), d'analogues d'AII, de fragments d'AII ou de leurs analogues ou d'agonistes de récepteur d'AII AT2 de type 2.
Dizerega Gere
Rodgers Kathleen E.
Dizerega Gere
Rodgers Kathleen E.
Smart & Biggar
University Of Southern California
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