Improved radiometal complex compositions

Details Improved radiometal complex compositions Improved radiometal complex compositions

A - Human Necessities

61

K

A61K 51/04 (2006.01) A61K 49/00 (2006.01) A61K 51/12 (2006.01) C07D 451/02 (2006.01)

Patent

CA 2514307

The present invention relates to stabilised technetium and rhenium metal complex compositions comprising a radioprotectant and a radiometal complex of a tropane-tetradentate chelating agent conjugate, wherein the radiometal complex is neutral. Radiopharmaceuticals comprising the stabilised metal complex compositions, and kits for the preparation of the radiopharmaceuticals are also described.

L'invention concerne des compositions stabilisées de complexes métalliques de technétium et de rhénium, ces compositions comprenant un agent radioprotecteur et un complexe de radiométal comprenant un conjugué d'agent chélateur tropane-tétradente, le complexe de radiométal étant neutre. La présente invention porte également sur des produits radiopharmaceutiques comportant les compositions stabilisées de complexes métalliques et sur des kits destinés à leur préparation.

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