Improved reduced irritant enema for the treatment of...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/609 (2006.01) A61J 1/05 (2006.01) A61K 9/08 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2677095

The present invention comprises packaged enemas for the treatment of Inflammatory Bowel Disease (IBD), having substantially pure 5-ASA as the active ingredient, with a liquid carrier medium having a material avoidance of bowel irritant substances, such as anti-oxidants for the 5-ASA active ingredient, including such sulfites as potassium metabisulfite, for example, and contained within a sealed and substantially oxygen-free barrier package, which may preferably be formed of a foil/polymer laminate, and which package contains or otherwise includes an oxygen scavenger, such as a an oxygen scavenging sachet.

La présente invention comprend des lavements emballés destinés au traitement d'une affection intestinale inflammatoire (IBD) qui renferment du 5-ASA pratiquement pur en tant qu'ingrédient actif, et un milieu véhicule liquide permettant de supprimer des substances irritantes pour l'intestin, tels que des antioxydants pour l'ingrédient actif de 5-ASA; qui comprennent des sulfites tel que le métabisulfite de potassium, par exemple; et qui sont contenus dans un emballage barrière scellé et pratiquement sans oxygène pouvant être de préférence formé d'un stratifié aluminium/polymère, ledit emballage contenant ou intégrant un désoxygénant, tel qu'un sachet piégeant l'oxygène.

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