Improved release of medicament active agents from a chewing...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/68 (2006.01) A23G 3/00 (2006.01) A23G 3/02 (2006.01) A61K 9/28 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2355779

A method for producing a chewing gum with an improved release of active agent, as well as the chewing gum so produced, is obtained by adding an active agent to a chewing gum coating. The active agent is added to the coating in a coating solution or premixed with a flavor or solvent. The coating solution may contain sweetener or other transdermal enhancing agents to obtain increased transmucosal absorption. An active agent may also be used in the gum core.

La présente invention un procédé de production d'un chewing-gum permettant de mieux libérer un agent actif, et concerne également le chewing-gum ainsi produit. On obtient ce chewing-gum en ajoutant un agent actif à l'enrobage d'un chewing-gum. On ajoute l'agent actif à l'enrobage dans une solution d'enrobage, ou en le prémélange avec un arôme ou un solvant. La solution d'enrobage peut contenir un édulcorant ou d'autres agents stimulateurs transdermiques pour augmenter l'absorption transmuqueuse. Par ailleurs, on peut utiliser un agent actif dans la partie centrale du chewing-gum.

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