C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 339/04 (2006.01) C07C 323/12 (2006.01) C07C 323/52 (2006.01) C07C 331/10 (2006.01) C07D 339/08 (2006.01) C07K 7/28 (2006.01) C08B 37/00 (2006.01) G01N 27/327 (2006.01) G01N 27/333 (2006.01)
Patent
CA 2254072
The present invention provides linker lipids for use in attaching a membrane including a plurality of ionophores to an electrode and providing a space between the membrane and the electrode. The membrane is either in part or totally made up of the linker lipid. The linker lipid comprises within the same molecule a hydrophobic region capable of spanning at least half the membrane, an attachment group used to attach the molecule to an electrode surface, a hydrophilic region intermediate said hydrophobic region and the attachment group, and a polar head group region attached to the hydrophobic region at a site remote from the hydrophilic region wherein said attachment group has a cross-sectional area that is at least two times the cross- sectional area of the hydrophilic region.
L'invention porte sur des lipides de liaison servant à attacher une membrane comportant plusieurs ionophores à une électrode tout en laissant un espace entre la membrane et l'électrode. La membrane est constituée en tout ou en partie par le lipide de liaison. Le lipide de liaison comporte à l'intérieur d'une même molécule une zone hydrophobe pouvant couvrir au moins la moitié de la membrane, un groupe de fixation servant à attacher la molécule à la surface de l'électrode, une zone hydrophile entre la zone hydrophobe et le groupe de fixation, un groupe polaire de tête fixé à la zone hydrophobe en un site distant de la zone hydrophile, ledit groupe de fixation présentant une section au moins deux fois celle de la zone hydrophile.
Burns Christopher John
Field Leslie David
Raguse Burkhard
Ridley Damon Donald
Ambri Limited
Australian Membrane And Biotechnology Research Institute
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The University Of Sydney
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