Improved sensor membranes

Details Improved sensor membranes Improved sensor membranes

C - Chemistry, Metallurgy

07

C

C07C 323/12 (2006.01) B01D 69/12 (2006.01) B01D 69/14 (2006.01) C07C 43/23 (2006.01) C07D 495/04 (2006.01) C07F 9/10 (2006.01) C07H 15/08 (2006.01) C07K 2/00 (2006.01) C12M 1/40 (2006.01) C12Q 1/00 (2006.01) G01N 27/327 (2006.01) G01N 27/333 (2006.01) G01N 27/40 (2006.01) G01N 31/22 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2145996

The present invention relates to electrode membrane combinations for use in ion selective electrodes and biosensors. In ad- dition, the present invention relates to methods for the production of such electrode membrane combinations and the use of ion selective electrodes and biosensors incorporating such electrode membrane combinations in the detection of analytes. The present invention also relates to novel compounds used in the electrode membrane combinations. These novel compounds include a link- er lipid for use in attaching a membrane including a plurality of ionophores to an electrode and providing a space between the membrane, the electrode being either in part or totally made up of the linker lipid. The linker lipid comprises within the same molecule a hydrophobic region capable of spanning the membrane, an attachment group used to attach the molecule to an elec- trode surface, a hydrophilic region intermediate said hydrophobic region and the attachment group, and a polar head group re- gion attached to the hydrophobic region at a site remote from the hydrophilic region.

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