Improved snuff composition

Details Improved snuff composition Improved snuff composition

A - Human Necessities

61

K

A61K 9/14 (2006.01) A24B 15/14 (2006.01) A61K 31/465 (2006.01)

Patent

CA 2646942

Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test, about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.

L'invention concerne l'utilisation d'une combinaison nicotine-cellulose dans la préparation d'une composition de tabac à priser qui permet d'obtenir rapidement l'effet de la nicotine après son application dans la cavité buccale du sujet. Etant donnée sa vitesse de libération élevée, la composition libère 45% au moins de sa teneur totale en nicotine dans les 30 minutes lorsqu'elle est soumise à un essai de dissolution in vitro. Par ailleurs, l'invention concerne une composition améliorée de tabac à priser qui s'applique dans la cavité buccale.

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