Improved solvent systems

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/38 (2006.01) C07F 9/553 (2006.01)

Patent

CA 2391785

In a method for making bisphosphonates by reacting a carbonyl compound with a phosphorus halide, the reaction is carried out in a solvent/carrier system comprising an amine hydrochloride, phosphorous acid and optionally phosphoric acid.

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