Improved synthesis and preparations of duloxetine salts

Details Improved synthesis and preparations of duloxetine salts Improved synthesis and preparations of duloxetine salts

C - Chemistry, Metallurgy

07

D

C07D 333/20 (2006.01)

Patent

CA 2634008

The invention relates to an improved process for the preparation of duloxetine hydrochloride. More particularly, the invention relates to a process for the enantiomeric enrichment of duloxetine, and to a process for increasing the enantiomeric excess of enantiomerically-enriched duloxetine and salts thereof. Image

La présente invention concerne un procédé perfectionné destiné à la préparation d'un hydrochlorure de duloxétine. L'invention porte plus spécifiquement sur un procédé destiné à l'enrichissement énantiomère de la duloxétine, ainsi qu'à un procédé destiné à augmenter un excès énantiomère de la duloxétine enrichie en énantiomères et de ses sels.

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