Improved synthesis of ioversol

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 237/46 (2006.01) C07C 231/10 (2006.01) C07C 231/12 (2006.01) C07C 231/24 (2006.01)

Patent

CA 2134653

2134653 9323365 PCTABScor01 The reduction of the O-alkyl isomer content of 5-[N-(2-acetoxyethyl)acetoxyacetamido]-N,N'-bis(2,3-diacetoxypropyl)-2,4,6-tr_ iiodoisophthalamide to thereby reduce and/or eliminate the production of impurities comparatively more difficult to remove during the purification of crude ioversol.

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