Improved synthetic lipid mixtures for the preparation of a...

Details Improved synthetic lipid mixtures for the preparation of a... Improved synthetic lipid mixtures for the preparation of a...

C - Chemistry, Metallurgy

07

K

C07K 14/785 (2006.01) A61K 38/17 (2006.01) A61P 11/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2486152

The invention relates to reconstituted surfactants consisting of artificial phospholipids and peptides able to lower the air-liquid surface tension, more particularly to reconstituted surfactants, comprising special phospholipid mixtures and artificial peptides which are analogues of the natural surfactant SP-C protein for the treatment of respiratory distress syndrome (RDS) and other diseases relates to pulmonary surfactant dysfunctions.

L'invention concerne des tensioactifs reconstitués comprenant des phospholipides et des lipides artificiels améliorés capables d'abaisser la tension superficielle à l'interface air-liquide, plus particulièrement des tensioactifs reconstitués comprenant des mélanges phospolipidiques spéciaux et des peptides artificiels qui sont des analogues de la protéine naturelle SP-C. Ces tensioactifs sont destinés au traitement du syndrome respiratoire aigu sévère (SRAS) et autres pathologies associées à des dysfonctionnements de tensioactifs pulmonaires.

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