A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/36 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2458856
The present invention relates to the field of chemotherapy of diseases such as cell proliferation disorders including cancer. In particular, the present invention relates to the use of hyaluronan (HA) as a protective agent in the treatment of subjects. HA is administered in conjunction with a chemotherapeutic agent to facilitate the prolonged administration of a dose of the chemotherapeutic agent to be administered to a subject. Owing to the protective effects of the HA, the dose of chemotherapeutic agent may be substantially higher than a generally accepted effective dose, which would otherwise be expected to cause unacceptable side effects in the subject.
La présente invention concerne le domaine de la chimiothérapie de maladies telles que les troubles de la prolifération cellulaire, y compris le cancer. L'invention concerne en particulier l'utilisation d'hyaluronan (HA) comme agent protecteur dans le traitement des patients. Le HA est administré conjointement à un agent chimiothérapeutique afin de faciliter l'administration prolongée d'une dose de l'agent chimiothérapeutique à administrer au patient. En raison des effets protecteurs du HA, la dose de l'agent chimiothérapeutique peut être sensiblement supérieure à une dose efficace généralement acceptée, mais serait autrement considérée susceptible de générer des effets secondaires inacceptables chez le patient.
Brown Tracey Jean
Fox Richard Mark
Alchemia Oncology Pty Limited
Meditech Research Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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