Improved thin film biosensor and method and device for...

G - Physics – 01 – N

Patent

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G01N 33/53 (2006.01)

Patent

CA 2634066

Thin-film biosensor chips for detecting a target analyte in a biological sample are disclosed. The chips include a solid substrate, an antireflective optical layer, an attachment layer using a non-polymeric silane, and an Fc-specific binding molecule coupled to the non-polymeric silane. Kits containing the chips and methods of using and making the chips are also disclosed.

La présente invention concerne des puces de biocapteurs à pellicule mince servant à détecter une substance cible à analyser dans un échantillon biologique. Les puces comprennent un substrat solide, une couche optique antireflet, une couche d'attache utilisant un silane non polymère, et une molécule liante spécifique au Fc couplée au silane non polymère. La présente invention concerne également des ensembles contenant les puces et des procédés d'utilisation et de fabrication des puces.

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