Improved topical drug delivery composition and method

Details Improved topical drug delivery composition and method Improved topical drug delivery composition and method

A - Human Necessities

61

K

A61K 31/203 (2006.01) A61K 8/02 (2006.01) A61K 8/67 (2006.01) A61K 9/06 (2006.01) A61K 31/07 (2006.01) A61K 31/232 (2006.01) A61P 17/00 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2396044

A topical composition for delivering an effetive amount of a pharmaceutically acceptable drug, including laureth-4, propylene glycol, dimethylsorbide, and a pharmaceutically acceptable diluent is described as an improved drug delivery composition. Further, a method of transepithelial delivery of a drug to a human by topical application to the skin of a human of a composition including laureth-4, propylene glycol, dimethylsorbide, a pharmaceutically acceptable diluent of water and ethanol and an effective amount of a pharmaceutically acceptable drug has beneficial delivery effects.

La présente invention concerne une composition topique améliorée utilisée pour administrer une dose efficace d'un médicament acceptable sur le plan pharmaceutique, contenant laureth-4, propylène glycol, diméthylsorbide, et un diluent acceptable sur le plan pharmaceutique. Par ailleurs, cette invention concerne un procédé d'administration trans-épithéliale d'un médicament à un sujet humain par application topique sur la peau d'une composition contenant laureth-4, propylène glycol, diméthylsorbide, un diluent d'eau et d'éthanol acceptable sur le plan pharmaceutique et une dose efficace d'un médicament acceptable sur le plan pharmaceutique, ce procédé présentant des effets bénéfiques d'administration.

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