Improved toxicity screening method

Details Improved toxicity screening method Improved toxicity screening method

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/554 (2006.01)

Patent

CA 2383987

The present invention provides materials and methods for predicting the in vivo toxicity of a given compound. For example, the invention comprises conducting at least three distinct assays in parallel to provide information about three distinct parameters of cytotoxicity of a chemical in a given target cell, which information is useful for predicting in vivo cytotoxicity.

La présente invention concerne des matières et des procédés servant à une évaluation préliminaire de la toxicité in vivo d'un composé donné. Selon un mode de réalisation, cette invention peut consister à effectuer trois analyses différentes en parallèle pour obtenir des informations concernant trois paramètres distincts de cytotoxicité d'un produit chimique dans une cellule cible donnée. Ces informations sont utiles pour effectuer une évaluation préliminaire de la cytotoxicité in vivo.

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