C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/47 (2006.01) A61K 39/155 (2006.01) A61K 39/205 (2006.01) C07K 14/115 (2006.01) C07K 14/145 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/45 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2113572
2113572 9301833 PCTABS00019 A virus like particle (VLP) containing an RNA genome including a 3' domain and a filler domain surrounded by a sheath of rabies M protein or similar protein from a rhabdovirus or paramyxovirus and rabies M1 protein or similar protein from a rhabdovirus or paramyxovirus to form a ribonucleo protein complex. The VLP also includes a lipid envelope of rabies G protein or similar protein from a rhabdovirus or paramyxovirus and an internal matrix of rabies M2 protein or similar protein from a rhabdovirus or paramyxovirus. There is also included a process for constructing the VLP and also a vaccine for treatment of rhabdovirus and paramyxovirus infection which utilises the aforementioned VLPs in association with an adjuvant. There is also included a DNA construct for use in the abovementioned process.
Prehaud Christophe J.
Walker Peter J.
Commonwealth Scientific And Industrial Research Organisation
Ridout & Maybee Llp
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