Improved vaccines against bordetella pertussis based on lps...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/235 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2681924

The invention relates to an improved vaccine against pertussis wherein mutants of Bordetella pertussis having a modified LPS molecule or the obtainable LPS molecules are used. These mutants or the obtainable LPS molecules may further be used as an adjuvant.

La présente invention concerne un vaccin anticoquelucheux amélioré dans lequel sont utilisés des mutants de Bordetella pertussis ayant une molécule LPS modifiée ou bien les molécules LPS peuvant être obtenues à partir de ces mutants. Ces mutants ou les molécules LPS pouvant être obtenues à partir de ceux-ci peuvent en outre être utilisés comme adjuvants.

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