C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/37 (2006.01) A61K 31/7052 (2006.01) A61K 31/7088 (2006.01) A61K 39/12 (2006.01) A61P 31/20 (2006.01) A61P 37/04 (2006.01) C07K 14/025 (2006.01) C12N 7/01 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2749120
anti-HPV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HPV 18 E6 and E7. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HPV are disclosed.
L'invention concerne des immunogènes anti-HPV améliorés et des molécules d'acides nucléiques qui les codent. Les immunogènes de l'invention comprennent ceux qui ont la séquence fondamentale HPV 18 E6 et E7. Une composition pharmaceutique, des vaccins recombinants et des vaccins atténués vivants sont décrits, ainsi que des procédés pour induire une réponse immunitaire contre le HPV chez un individu.
Weiner David B.
Yan Jian
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of The University Of Pennsylvania
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