C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 35/12 (2006.01) A61K 35/28 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2157931
Improved recombinant retrotransposon vectors for gene transfer are disclosed. The synthetic vectors are truncated so as to reduce or altogether eliminate homologous recombination with retroviral helper sequences found in helper cells used to propagate the vectors, making them safer for use in humans and providing more space for therapeutic genes. The vectors transmit foreign DNA efficiently, are stable, enable abundant RNA expression from the retrotransposon transcriptional promoter, and through their diversity permit many useful applications in therapeutics and transgenics. Methods are described for rescuing tissue-specifics obtaining expression in primary cells, mapping the genome and other techniques of therapeutic and transgenic utility.
Creighton University
Gowling Lafleur Henderson Llp
LandOfFree
Improved vectors for gene therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Improved vectors for gene therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Improved vectors for gene therapy will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1826492