Improvement in ionic reservoir through application of an...

G - Physics – 01 – N

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G01N 27/26 (2006.01) C12Q 1/00 (2006.01) G01N 27/327 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2221307

The present invention provides an improved membrane based biosensor comprising a lipid membrane incorporating ionophores the conductivity of the membrane being dependent on the presence or absence of an analyte, a reference electrode, a sensing electrode on to which is deposited the lipid membrane such that a functional reservoir exists between the lipid membrane and the sensing electrode. The improvement comprises including in the biosensor means to apply a dc electrical potential offset to the sensing electrode relative to the reference electrode.

La présente invention concerne un biodétecteur basé sur une membrane lipidique améliorée comprenant des ionophores, la conductivité de la membrane étant dépendante de la présence ou de l'absence d'un analyte, une électrode de référence, une électrode de détection sur laquelle est déposée la membrane lipidique, un réservoir fonctionnel étant formé entre la membrane lipidique et l'électrode de détection. L'amélioration consiste à incorporer dans le biodétecteur un moyen destiné à appliquer un courant électrique continu provoquant un décalage du potentiel de l'électrode de détection par rapport à l'électrode de référence.

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