Improvement to bilirubin assay by using crosslinkable polymers

Details Improvement to bilirubin assay by using crosslinkable polymers Improvement to bilirubin assay by using crosslinkable polymers

G - Physics

01

N

G01N 33/72 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2094452

A colorimetric assay for the determination of conjugated or unconjugated bilirubin in biological fluids can be carried out with an improved analytical element. The element comprises a support having thereon a gelatin-free mordant layer comprising a positively-charged interactive mordant having at least one binding site for bilirubin, a radiation-blocking layer, and a porous spreading layer. The interactive mordant is dispersed in a binder material of crosslinkable copolymers which include a monomer capable of reaction with a crosslinking agent to crosslink the copolymer.

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