Improvements in chemical compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 257/02 (2006.01) A61K 31/395 (2006.01) A61K 31/555 (2006.01) C07D 255/02 (2006.01) C07D 259/00 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 471/04 (2006.01) C07F 1/08 (2006.01) C07F 3/06 (2006.01)

Patent

CA 2125978

Linked cyclic polyamines of formula: Z - R - A - R' - Y, where Z and Y are each cyclic polyamine moieties, A is an aromatic or heteroaromatic moiety, and R and R' are each an alkylene chain or heteroatom-containing chain, show high activity against HIV, and low toxicity, in in vivo tests. Novel compounds, and pharmaceutical compositions are claimed.

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