Improvements in methods and devices to curb appetite and/or...

A - Human Necessities – 61 – N

Patent

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Details

A61N 1/375 (2006.01) A61B 17/00 (2006.01) A61L 31/14 (2006.01) A61M 31/00 (2006.01) A61L 31/02 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2652419

The present invention relates to devices and methods of operating the devices that contribute to curbing appetite and/or reducing food intake. In some embodiments, the methods and devices of the present invention include as intestinal/duodenal insert comprising an elongated member with at least one flow reduction element that can cause the stimulation of one or more biological signals of satiety. Some embodiments of the inserted device are anchored at the duodenal site by an anchoring member residing in the stomach, other embodiments of the device are stabilized at a targeted site by appropriate dimensions of length as well as one or more angled portions of the device that correspond to angled portions of the targeted site in the dodenum. Embodiments of the device exert effects by virtue of physical presence, as well as by more active forms of intervention, including release of bioactive materials and electrical stimulation of neurons.

L'invention concerne des dispositifs et des procédés d'utilisation de ces dispositifs qui contribuent à refréner l'appétit et/ou réduire l'ingestion alimentaire. Dans certains modes de réalisation, ces dispositifs et procédés comprennent un insert intestinal/duodénal comportant un élément allongé doté d'au moins un élément de réduction de flux qui peut provoquer la stimulation d'un ou de plusieurs signaux biologiques de satiété. Certains modèles du dispositif inséré sont ancrés dans le site du duodénum au moyen d'un élément d'ancrage se trouvant dans l'estomac. D'autres modèles du dispositif sont stabilisés dans un site cible par des longueurs dimensionnées de manière appropriée et par une ou plusieurs parties angulaires du dispositif correspondant à des parties angulaires du site cible dans le duodénum. Des réalisations de ce dispositif agissent par le seul fait de leur présence physique, mais aussi par des formes d'intervention plus actives, y compris par la libération d'agents bioactifs et par la stimulation électrique de neurones.

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