C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 19/00 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C40B 40/02 (2006.01)
Patent
CA 2196419
Disclosed are libraries of DNA sequences encoding zinc finger binding motifs for display on a particle, together with methods of designing zinc finger binding polypeptides for binding to a particular target sequence and, inter alia, use of designed zinc finger polypeptides for various in vitro or in vivo applications.
On décrit des banques de séquences d'ADN qui codent des motifs de liaison en doigt de zinc destinés à être fixés sur une particule, des procédés de conception de polypeptides de liaison en doigt de zinc destinés à se lier à une séquence cible particulière et, notamment, l'utilisation de polypeptides en doigt de zinc déterminés concernant différentes applications in vitro ou in vivo.
Choo Yen
Klug Aaron
Sanchez-Garcia Isidro
Gendaq Limited
Kirby Eades Gale Baker
Medical Research Council
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