C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/04 (2006.01) A61K 9/48 (2006.01) A61M 31/00 (2006.01) C12M 1/00 (2006.01)
Patent
CA 2302788
A controlled release capsule comprises a female body (10) having a charge receiving portion (15) for holding a charge (20) of an agent to be released. A water-swellable male plug member (25) is engaged within a neck portion (30) of the female body. Buoyancy means (45) are provided to keep the closed end of the female body uppermost, so that when the male member is released from the female body the buoyancy means cause the female body to orientate to facilitate release of the charge under gravity from the female body. The construction promotes rapid emptying of the charge from the capsule after swelling and disengagement of the male plug member.
Selon cette invention, une capsule pour libération contrôlée comporte un corps femelle (10) doté d'une partie (15) réceptrice de charge destinée à retenir une charge (20) d'un agent devant être libéré. Un organe mâle obturateur (25), qui gonfle au contact de l'eau, est inséré dans une partie col (30) du corps femelle. Un organe de flottaison (45) est destiné à maintenir l'extrémité fermée du corps femelle en haut, de sorte que lorsque l'organe mâle est libéré du corps femelle, l'organe de flottaison provoque l'inclinaison du corps femelle en vue de faciliter la libération à partir de ce dernier de la charge soumise à la gravité. Cet agencement favorise le vidage rapide de la charge contenue dans la capsule après le gonflement et la séparation de l'organe mâle obturateur.
Atkins Gerard
Hegarty Mark
Mcfarlane Stephen Donald
R.p. Scherer Corporation
Smart & Biggar
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