Improvements in or relating to organic compounds

Details Improvements in or relating to organic compounds Improvements in or relating to organic compounds

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2655725

Polyoma viral vector production cell line comprising a heterologous polynucleotide sequence that is capable of being transcribed into an RNA sequence that is capable of folding into double stranded RNA of at least 50 base pairs in length, methods of producing said cell line, uses thereof and recombinant polyoma viral vectors and nucleic acid sequences relating thereto.

La présente invention concerne une lignée cellulaire produisant des vecteurs de polyomavirus qui comprend une séquence polynucléotidique hétérologue qui est capable d'être transcrite en une séquence d'ARN capable de se plier en ARN double-brin d'une longueur d'au moins 50 paires de bases. L'invention concerne également des procédés de production de ladite lignée cellulaire, des utilisations de celle-ci et des vecteurs de polyomavirus recombinants et des séquences d'acides nucléiques apparentées à ceux-ci.

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