Improvements in pharmaceutical compositions

C - Chemistry – Metallurgy – 07 – C

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C07C 49/753 (2006.01) A61K 31/695 (2006.01) A61P 25/28 (2006.01) C07C 49/647 (2006.01) C07C 323/22 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2470060

Compounds of formulae (I) or (II): wherein R is a substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl aralkenyl, or aralkynyl group, that optionally includes at least one heteroatom in its carbon skeleton, and R1 and R2 are H, or an -OR3 group in which R3 is a substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl aralkenyl, or aralkynyl group containing 4-12 carbon atoms, that optionally includes at least one heteroatom in its carbon skeleton, and R1 and R2 cannot both be H, and their use in therapeutic methods.

L'invention concerne des composés représentés par les formules (I) ou (II): Dans lesdites formules, R est alkyle substitué ou non substitué, alcényle, alkynyle, aryle, aralkylaralcényle, ou un groupe aralkynyle, comprenant éventuellement au moins un hétéroatome dans son squelette de carbone, et R?1¿ et R?2¿ sont H, ou un groupe -OR?3¿ dans lequel R?3¿ est alkyle substitué ou non substitué, alcényle, alkynyle, aryle, aralkylaralcényle, ou un groupe aralkynyle qui a entre 4 et 12 atomes de carbone, comprenant éventuellement au moins un hétéroatome dans son squelette de carbone, et R?1¿ et R?2¿ ne peuvent pas être ensemble H. L'invention concerne également l'utilisation des composés considérés dans le cadre de procédés thérapeutiques.

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