Improvements in platinum complexes

Details Improvements in platinum complexes Improvements in platinum complexes

C - Chemistry, Metallurgy

07

F

C07F 15/00 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2147567

Pt(IV) complexes of formula I, Image where X is halide, pseudohalide or OH, R1 and R2 are H, C1 to C6 alkyl, cycloalkyl, aryl or R1NH2 is a heterocyclic hydrogen donor, and may be the same or different, R3 and R4 are H, C1 to C5 alkyl, cycloalkyl or aryl and may be the same or different, and R5 is H, Me or Et, have activity in vitro and in vivo against cancer cells.

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