Improvements in the synthesis of annamycin

Details Improvements in the synthesis of annamycin Improvements in the synthesis of annamycin

C - Chemistry, Metallurgy

07

H

C07H 15/252 (2006.01) C07H 1/00 (2006.01)

Patent

CA 2261144

An improved method for synthesis of Annamycin is described. The synthesis relies upon a method of selectively deacetylating the Annamycin precursor and purification of the deacetylated product by a filtration step. In addition, the method includes an improved method for desilylating the Annamycin precursor that utilizes acidic conditions. Lastly, improved purification methods of the final Annamycin product are disclosed. Annamycin and the precursor have the formulae: <see formula I> <see formula II>

Divulgation d'une méthode de synthèse améliorée de l'annamycine. Cette synthèse repose sur une méthode de désacétylation sélective du précurseur de l'annamycine et sur la purification du produit désacétylé par filtration. En outre, cette méthode comprend une étape de désilylation du précurseur de l'annamycine dans des conditions acides. Enfin, on divulgue des méthodes améliorées pour la purification du produit final. L'annamycine et ses précurseurs ont les formules suivantes : (voir formule I) (voir formule II)

Affiliated with

Also associated with

Rating

Improvements in the synthesis of annamycin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Improvements in the synthesis of annamycin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Improvements in the synthesis of annamycin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1433923